有机化学发展史.ppt

上传人:p** 文档编号:160727 上传时间:2023-03-03 格式:PPT 页数:17 大小:664KB
下载 相关 举报
有机化学发展史.ppt_第1页
第1页 / 共17页
有机化学发展史.ppt_第2页
第2页 / 共17页
有机化学发展史.ppt_第3页
第3页 / 共17页
有机化学发展史.ppt_第4页
第4页 / 共17页
有机化学发展史.ppt_第5页
第5页 / 共17页
有机化学发展史.ppt_第6页
第6页 / 共17页
有机化学发展史.ppt_第7页
第7页 / 共17页
有机化学发展史.ppt_第8页
第8页 / 共17页
有机化学发展史.ppt_第9页
第9页 / 共17页
有机化学发展史.ppt_第10页
第10页 / 共17页
亲,该文档总共17页,到这儿已超出免费预览范围,如果喜欢就下载吧!
资源描述

《有机化学发展史.ppt》由会员分享,可在线阅读,更多相关《有机化学发展史.ppt(17页珍藏版)》请在第壹文秘上搜索。

1、化学专业英语演讲有机化学发展史Development of organic chemistry and its impact on the development of science and technology有机合成的发展及其对科有机合成的发展及其对科学技术发展的影响学技术发展的影响First part : A brief historyPhase One: Infancy (Early 19th century - 1858) Chemical development of this period is the basis for the development of organic

2、chemistry. Lavoisier is known as the father of modern chemistry. Phase Two: Classic Period (1858-1916) During this period the emergence of a large number of well-known organic chemist.Figure character is a famous organic chemist Kekule and Vant Hoff. Phase III: Modern Age Organic Chemistry (1916 to

3、date) This is the theoretical basis of organic chemistry more perfect time.The most famous organic chemist is Woodward in this period , he was known as the father of modern organic chemistry. Second part: Advances in Organic Synthesis Organic Chemistry is a very important chemical sciences in the tw

4、o disciplines, is most closely associated with the chemical branch of human life, its development and the development of human society are closely related.(1)Reactions and synthesis metal participatingCH bond activation In addition to palladium and other precious metals rhodium catalyzed carbon-hydr

5、ogen bond activation【1,2,3】, the use of relatively inexpensive copper, iron and other metals to achieve carbon-hydrogen bond activation has also been a great concern. Such as N Jiao【4】realized copper-catalyzed aniline ortho CH bond activation to introduce an azide group.The coupled reaction L Liu by

6、 copper-catalyzed realized an alkyl halide the coupling reaction with secondary alkyl halides and Grignard reagent【5】.Metal-catalyzed asymmetric synthesis reaction Chiral nitrogen oxides metal complex X M Feng development in the unsaturated ketone chloramine reaction【6】, a ketone - Diazoamides elect

7、rophilic addition reaction【7】, asymmetric BaeyerVilliger oxidation reaction【8】, are reflected in very excellent choice .(2) Reactions and synthesis of non-metallic participation The chemists of our countrys fast track, there have been new results were published【9,10】, such as S Yie【11】 reported that

8、 cinchona alkaloids catalyzed , - unsaturated acid chloride azodicarboxylate and the reaction can be achieved - amination.Third part: Organic synthesis of technological development With the continuous development of science and technology, organic synthesis are more important, it developed in many f

9、ields like bionic biology, new energy development and new drugs play an irreplaceable role. (1) The importance of organic synthesis for drug discovery synthetic organic chemistry is crucial for rapid navigation of increasingly complex drugable chemical space【12】.It is also critical in determining di

10、scovery cycle times and development speeds associated with drug candidates【13】. Most new drugs are developed using organic synthesis methods suce as antidiabetic agent ertugliflozin【14】.(2) Effect of Organic Synthesis of bionics DNA-inspired organic chemistry has become a classic branch in bioorgani

11、c research【15】. In this area has developed into a new discipline - bionic organic chemistry.(3) Effect of organic synthesis of new energy discovery The new energy research and development has been the focus of modern scientific research, such as bio-diesel.References【1】Z H Guan, M Chen, Z H en J Am

12、Chem Soc , 2012,134: 17490 17493【2】P Xie, Y Xie, B Qian et al J Am Chem Soc , 2012,134: 9902 9905【3】 Zeng, C Fu, S Ma J Am Chem Soc , 2012, 134:9597 9600【4】C Tang, N Jiao J Am Chem Soc , 2012, 134: 18924 18927【5】C T Yang, Z Q Zhang, J Liang et al J Am Chem Soc ,2012, 134: 11124 11127【6】Y F Cai, X H

13、Liu, J Jiang et al J Am Chem Soc ,2011, 133: 5636 5639【7】W Li, X H Liu, X Y Hao et al J Am Chem Soc , 2011,133: 15268 15271【8】L Zhou, X H Liu, J Ji et al J Am Chem Soc , 2012,134: 17023 17026【9】K A Ahrendt, C J Borths, D W C MacMillan J Am ChemSoc , 2000, 122: 4243 4244【10】B List, A Lerner, C F Barb

14、as J Am Chem Soc ,2000, 122: 2395 2396【11】L T Shen, L H Sun, S Ye J Am Chem Soc , 2011,133: 15894 15897【12】Vincent Mascitti, Benjamin A. Thuma, Aaron C. Smith. Med. Chem. Commun.,2012, 4,101.【13】F. Lovering, J. Bikker and C. Humblet, Escape from Flatland: Increasing Saturation as an Approach to Improvinc Clinical Success, J. Med. Chem., 2009, 52, 6752.【14】A. Nadin, C. Hattotuwagama and I. Churcher, Leadoriented synthesis: a new opportunity for synthetic chemistry, Angew. Chem., Int. Ed., 2012, 51, 1114.【15】Salvador Tomas. Annu. Rep. Prog. Chem., Sect. B, 2011, 107, 390413.专英32翻译.pdfThank You

展开阅读全文
相关资源
猜你喜欢
相关搜索

当前位置:首页 > 办公文档 > PPT模板素材

copyright@ 2008-2023 1wenmi网站版权所有

经营许可证编号:宁ICP备2022001189号-1

本站为文档C2C交易模式,即用户上传的文档直接被用户下载,本站只是中间服务平台,本站所有文档下载所得的收益归上传人(含作者)所有。第壹文秘仅提供信息存储空间,仅对用户上传内容的表现方式做保护处理,对上载内容本身不做任何修改或编辑。若文档所含内容侵犯了您的版权或隐私,请立即通知第壹文秘网,我们立即给予删除!